New screening technology will help to produce high efficiency drug to curing cancer

New screening technology will help to produce high efficiency drug to curing cancer


Cancer cell line panel screening

March 30, 2015-America-Scientist has been trying to cure cancer by killing tumor cells. Recently, the research team at chempartner.com which is the famous

Antibody Drug Discovery services supplier presented an alternative anti-cancer strategy which is increasing the hardness of cancer cells surface and then preventing them spreading to other parts of the body. They found one new compound which could help to achieve this goal by screening and then they also test the therapeutic potential of this pancreatic cancer compound. The results have been already published in the PNAS journal PNAS.

"Many cancer drugs face with the problem of side effects and cancer resistance. However, the new treatment regimen can largely avoid these problems," said Professor from chempartner.com. "In addition, we also developed the new Cancer cell line panel screening system which can also help people to find potential drugs to treat other diseases."

This technician also notes that the cell morphological changes have directly relation with many diseases which including cancer, neurodegenerative diseases, chronic obstructive pulmonary disease and the others. Compounds which products by the


href="https://www.chempartner.com/" _fcksavedurl="https://www.chempartner.com/">novel antibody drug discovery is expected to prevent the development of these diseases.

Prior to their research, the majority of those screening drug were prefer to look for disease-related pathways small molecules. However, their new screening method is based on the final performance of the entire cell. They use small molecules to treat the Dictyostelium discoideum which just likes the mammalian cell. Under normal circumstances, Dictyostelium discoideum only has two nuclei appearing in the process of division. If the proportion of multinucleated cells is relatively high, it means that the small molecule affects the process of cell division.

The researchers found 25 compounds in the above thousands small molecule in which 4-HAP can affect myosin II which is the cytoskeletal components of cells. In the development of pancreatic cancer, the cancer cells will be spread to other parts of body from the primary tumor cells. Studies have shown that the invasion pancreatic cancer cells will be more easily deformed and this characteristic has directly relationship with myosin II.

Currently, 4-HAP is being tested with mice by famous Cancer cell line panel screening services supplier www.chempartner.com. This drug has been used to treat jaundice in some countries. If the mouse experiment is successful, then the 4-HAP will be able to enter clinical rate.

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